At large with life blog
I did my PhD in Keith Lindsey’s lab, working on hormone responses in drought and how they regulate root growth. I came to work for Stuart in February 2016. I work with Nick characterise the molecular mechanisms involved in light regulated stomatal development. Plants lacking the light receptor PhyB are more water use efficient, meaning they use less water to fix a given amount of carbon. Understanding why this is so may help breeders produce crops that use less water, without compromising on yield.
We use a variety of molecular and physiological techniques to better understand why light insensitive mutants have better water use efficiency. These including gene expression analysis, genetics, confocal microscopy, carbon isotope discrimination, infra red gas analysis, chlorophyll fluorescence and mathematical modelling.
- Rowe, J., Topping J.F., Liu, J., Lindsey, K. Abscisic acid regulates root growth under osmotic stress conditions via an interacting hormonal network with cytokinin, ethylene and auxin. New Phytologist 1469-8137
- Liu, J. Rowe, J., Lindsey, K., (2014). Hormonal crosstalk for root development: a combined experimental and modelling perspective. Frontiers in Plant Science 5.
- Vernon, I., Goldstein, M., Rowe, J., Topping, JF., Liu, J., Lindsey , K., Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions. (Under review in BMC Systems Biology, available as preprint: https://arxiv.org/abs/1607.06358 ).
- Moore, S.P.M., Zhang, X., Mudge, A., Rowe, J., Topping, J.F., Liu, J., and Lindsey, K. (2015) Spatiotemporal modelling of hormonal crosstalk explains the level and patterning of hormones and gene expression in Arabidopsis thaliana wildtype and mutant roots. New Phytologist 207: 1110–1122.
- Mehdi, S., Mudge, A., Rowe, J., Liu, J., Topping, J.F. & Lindsey, K. (2016). The POLARIS Peptide: Role in Hormone Signalling and Root Growth. In Annual Plant Reviews: Peptide Signals in Plants. Huffaker, A. & Pearce, G. Wiley-Blackwell. in press.
- International Study Group on Systems Biology, Speaker prize 2014
- New Phytologist Next Generation Scientists, Runner up Poster prize 2014
- Durham University Research away day, Poster prize 2015